node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F43G6.5 | cgh-1 | F43G6.5.1 | C07H6.5.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.414 |
F43G6.5 | cpb-1 | F43G6.5.1 | C40H1.1.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis. | 0.762 |
F43G6.5 | cpb-3 | F43G6.5.1 | B0414.5.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis. | 0.797 |
F43G6.5 | gld-2 | F43G6.5.1 | ZC308.1a.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Poly(A) RNA polymerase gld-2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. Acts as a regulator of mitosis/meiosis required for progression through meiotic prophase during oogenesis and spermatogenesis and for promotion of the entry into meiosis from the mitotic cell cycle. May act by regulating and activating gld-1 mRNA activity in germline. | 0.967 |
F43G6.5 | gld-3 | F43G6.5.1 | T07F8.3a.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | 0.950 |
F43G6.5 | ifet-1 | F43G6.5.1 | F56F3.1.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Translational repressor ifet-1; Involved in translational repression of multiple mRNAs in the distal gonad. Recruited to the 3' untranslated region (UTR) of zif-1 by oma-1 and is required for translational repression of zif-1. May also be involved in translational repression of mei-1 through recruitment to the mei-1 3' UTR by oma-1. Required for oogenesis but not spermatogenesis, for P granule formation and for the localization of car-1 and cgh-1 to P granules. Required for normal spindle orientation in early embryos. | 0.426 |
F43G6.5 | pap-1 | F43G6.5.1 | Y32F6A.3.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | 0.904 |
F43G6.5 | symk-1 | F43G6.5.1 | F25G6.2.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | SYMpleKin cleavage and polyadenylation factor. | 0.991 |
car-1 | cgh-1 | Y18D10A.17.1 | C07H6.5.1 | Cytokinesis, Apoptosis, RNA-associated. | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.999 |
car-1 | cpb-1 | Y18D10A.17.1 | C40H1.1.1 | Cytokinesis, Apoptosis, RNA-associated. | Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis. | 0.633 |
car-1 | cpb-3 | Y18D10A.17.1 | B0414.5.1 | Cytokinesis, Apoptosis, RNA-associated. | Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis. | 0.870 |
car-1 | ifet-1 | Y18D10A.17.1 | F56F3.1.1 | Cytokinesis, Apoptosis, RNA-associated. | Translational repressor ifet-1; Involved in translational repression of multiple mRNAs in the distal gonad. Recruited to the 3' untranslated region (UTR) of zif-1 by oma-1 and is required for translational repression of zif-1. May also be involved in translational repression of mei-1 through recruitment to the mei-1 3' UTR by oma-1. Required for oogenesis but not spermatogenesis, for P granule formation and for the localization of car-1 and cgh-1 to P granules. Required for normal spindle orientation in early embryos. | 0.998 |
cgh-1 | F43G6.5 | C07H6.5.1 | F43G6.5.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | 0.414 |
cgh-1 | car-1 | C07H6.5.1 | Y18D10A.17.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Cytokinesis, Apoptosis, RNA-associated. | 0.999 |
cgh-1 | cpb-1 | C07H6.5.1 | C40H1.1.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis. | 0.771 |
cgh-1 | cpb-3 | C07H6.5.1 | B0414.5.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Cytoplasmic polyadenylation element-binding protein 3; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs (By similarity). May not be required for oogenesis. | 0.960 |
cgh-1 | daz-1 | C07H6.5.1 | F56D1.7.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | DAZ protein 1; RNA-binding protein that plays a central role in oogenesis, but not for spermatogenesis. Required for meiotic entry and germline differentiation, at the pachytene stage of meiosis I of female germline regardless of the sex of the soma. May act by regulating translation of specific mRNAs, possibly by binding to their 3'-UTR. | 0.547 |
cgh-1 | gld-2 | C07H6.5.1 | ZC308.1a.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Poly(A) RNA polymerase gld-2; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. Acts as a regulator of mitosis/meiosis required for progression through meiotic prophase during oogenesis and spermatogenesis and for promotion of the entry into meiosis from the mitotic cell cycle. May act by regulating and activating gld-1 mRNA activity in germline. | 0.428 |
cgh-1 | gld-3 | C07H6.5.1 | T07F8.3a.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | 0.550 |
cgh-1 | ifet-1 | C07H6.5.1 | F56F3.1.1 | ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Translational repressor ifet-1; Involved in translational repression of multiple mRNAs in the distal gonad. Recruited to the 3' untranslated region (UTR) of zif-1 by oma-1 and is required for translational repression of zif-1. May also be involved in translational repression of mei-1 through recruitment to the mei-1 3' UTR by oma-1. Required for oogenesis but not spermatogenesis, for P granule formation and for the localization of car-1 and cgh-1 to P granules. Required for normal spindle orientation in early embryos. | 0.999 |