STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gly-13Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans (By similarity); Belongs to the glycosyltransferase 13 family. (449 aa)    
Predicted Functional Partners:
M70.4
Uncharacterized protein.
   
  
 0.964
aman-2
Alpha-mann_mid domain-containing protein.
   
 
 0.937
gly-12
UDP-N-acetylglucosamine:a-3-D-mannoside b-1,2-N-acetylglucosaminyltransferase I.
  
 
0.926
mans-2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity).
   
 0.924
mans-1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 0.923
mans-4
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
     
 0.918
gly-14
UDP-N-acetylglucosamine:a-3-D-mannoside b-1,2-N-acetylglucosaminyltransferase I.
  
  
0.906
gly-20
GLYcosylation related.
   
  
 0.887
fut-6
Alpha-(1,3)-fucosyltransferase fut-6; Involved in the fucosylation of N-glycans. Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the distal GlcNAc residue in N-glycans. Catalyzes the transfer of fucose to Gal-beta-1-4-GlcNAc-alpha-pNP (LN-pNP) and Gal- beta-1-4-GlcNAc-beta-1-3-Gal-beta-1-4-Glc (LNnT). Unlike alpha-(1,3)-fucosyltransferase fut-1, does not transfer fucose to Man-alpha-1-3-(Man-alpha-1-6)-Man-beta-1-4-GlcNAc-beta-1-4-GlcNAc- beta-1-Asn (M3), Man-alpha-1-3-(Man-alpha-1-6)-Man-beta-1-4-GlcNAc- beta-1-4-(Fuc-alpha-1-6)-GlcNAc-beta-1-Asn (M3F6) and Glc [...]
      
 0.827
gly-17
GLYcosylation related.
      
 0.815
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.