Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| lin-15A | lin-35 | ZK678.1.2 | C32F10.2.1 | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | 0.704 |
| lin-15A | lin-37 | ZK678.1.2 | ZK418.4.1 | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | Uncharacterized protein. | 0.669 |
| lin-15A | lin-38 | ZK678.1.2 | Y48E1B.7.1 | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | C2H2-type domain-containing protein. | 0.764 |
| lin-15A | lin-56 | ZK678.1.2 | ZK673.3.1 | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | Protein lin-56; Required for translation, stability and/or localization of lin-15a. | 0.942 |
| lin-15A | lin-8 | ZK678.1.2 | B0454.1.1 | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | Protein lin-8; Acts as a synthetic multivulva class A (synMuvA) protein and redundantly inhibits lin-3/EGF expression to prevent inappropriate vulva induction. | 0.856 |
| lin-15A | lin-9 | ZK678.1.2 | ZK637.7b.1 | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | Protein lin-9; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. Required for the development of sheath cells in the hermaphrodite gonad and for the development of the male spicule, rays and gonad. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. | 0.700 |
| lin-35 | lin-15A | C32F10.2.1 | ZK678.1.2 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | 0.704 |
| lin-35 | lin-37 | C32F10.2.1 | ZK418.4.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Uncharacterized protein. | 0.978 |
| lin-35 | lin-38 | C32F10.2.1 | Y48E1B.7.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | C2H2-type domain-containing protein. | 0.500 |
| lin-35 | lin-52 | C32F10.2.1 | ZK632.13a.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Protein lin-52; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis. Belongs to the lin-52 family. | 0.997 |
| lin-35 | lin-56 | C32F10.2.1 | ZK673.3.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Protein lin-56; Required for translation, stability and/or localization of lin-15a. | 0.623 |
| lin-35 | lin-8 | C32F10.2.1 | B0454.1.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Protein lin-8; Acts as a synthetic multivulva class A (synMuvA) protein and redundantly inhibits lin-3/EGF expression to prevent inappropriate vulva induction. | 0.753 |
| lin-35 | lin-9 | C32F10.2.1 | ZK637.7b.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Protein lin-9; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. Required for the development of sheath cells in the hermaphrodite gonad and for the development of the male spicule, rays and gonad. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. | 0.998 |
| lin-35 | lsy-2 | C32F10.2.1 | F49H12.1a.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Uncharacterized protein. | 0.578 |
| lin-37 | lin-15A | ZK418.4.1 | ZK678.1.2 | Uncharacterized protein. | Protein lin-15A; Synthetic multivulva (synMuv) class A protein. SynMuv proteins are required to repress the induction of vulval development. Acts redundantly with SynMuv class B protein lin-15B, and lin-35 to negatively regulate vulval development, most likely through antagonization of the Ras-signaling pathway. May also negatively regulate vulval development in association with other SynMuv class B proteins such as dpl-1 and efl-1. Regulates let-23 basal activity. Required for the correct expression and/or stability of lin-56. | 0.669 |
| lin-37 | lin-35 | ZK418.4.1 | C32F10.2.1 | Uncharacterized protein. | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | 0.978 |
| lin-37 | lin-38 | ZK418.4.1 | Y48E1B.7.1 | Uncharacterized protein. | C2H2-type domain-containing protein. | 0.535 |
| lin-37 | lin-52 | ZK418.4.1 | ZK632.13a.1 | Uncharacterized protein. | Protein lin-52; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis. Belongs to the lin-52 family. | 0.997 |
| lin-37 | lin-8 | ZK418.4.1 | B0454.1.1 | Uncharacterized protein. | Protein lin-8; Acts as a synthetic multivulva class A (synMuvA) protein and redundantly inhibits lin-3/EGF expression to prevent inappropriate vulva induction. | 0.549 |
| lin-37 | lin-9 | ZK418.4.1 | ZK637.7b.1 | Uncharacterized protein. | Protein lin-9; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. Required for the development of sheath cells in the hermaphrodite gonad and for the development of the male spicule, rays and gonad. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. | 0.997 |
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