STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0454.6AA_permease_C domain-containing protein. (585 aa)    
Predicted Functional Partners:
gst-27
Glutathione S-Transferase.
   
  
 0.698
catp-5
Cation-transporting ATPase catp-5; Involved in the uptake and/or transport of polyamines, probably through ATP hydrolysis. This contributes to the maintenance of intracellular polyamine levels. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
   
 
 0.694
C23H4.6
AAA_23 domain-containing protein.
     
 0.693
C35A5.3
MFS domain-containing protein.
      
 0.692
ugt-10
UDP-GlucuronosylTransferase.
      
 0.692
sulp-5
STAS domain-containing protein.
   
 
 0.690
gst-2
Glutathione S-transferase 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Sigma family.
   
  
 0.670
ugt-3
UDP-GlucuronosylTransferase.
      
 0.669
best-7
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
      
 0.664
ugt-5
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.663
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.