node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0511.2 | damt-1 | B0511.2.1 | C18A3.1.1 | annotation not available | DNA N6-methyl methyltransferase; Methylates DNA on the 6th position of adenine (N(6)- methyladenosine). N(6)-methyladenosine (m6A) DNA is involved in epigenetic transgenerational inheritance. Belongs to the MT-A70-like family. | 0.671 |
B0511.2 | dyf-5 | B0511.2.1 | M04C9.5b.1 | annotation not available | Serine/threonine-protein kinase dyf-5; Serine/threonine-protein kinase which is required for ciliogenesis. Regulates the length and the morphology of sensory neuron cilia. In addition, plays a role in the anterograde intraflagellar transport (IFT) in the cilia by regulating the undocking of kinesin-II motor complex (composed of klp-11, klp-20 and kap-1) before reaching the distal segment and the docking of kinesin motor osm-3 onto IFT cargos; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. RCK subfamily. | 0.550 |
B0511.2 | eif-3.H | B0511.2.1 | C41D11.2.1 | annotation not available | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.697 |
B0511.2 | jac-1 | B0511.2.1 | Y105C5B.21e.1 | annotation not available | Juxtamembrane domain-associated catenin; May act as a positive modulator of hmr-1 function during epidermal morphogenesis. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the beta-catenin family. | 0.637 |
B0511.2 | mett-10 | B0511.2.1 | ZK1128.2a.1 | annotation not available | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA) (By similarity). Involved in mRNA splicing (By similarity). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo. Belongs to the methyltransferase superfamily. METTL16/RlmF family. | 0.707 |
B0511.2 | mtq-2 | B0511.2.1 | C33C12.9.1 | annotation not available | MTS domain-containing protein. | 0.552 |
B0511.2 | pash-1 | B0511.2.1 | T22A3.5a.1 | annotation not available | PArtner of DroSHa (DRSH-1 interactor). | 0.681 |
B0511.2 | rict-1 | B0511.2.1 | F29C12.3b.1 | annotation not available | RICTOR_V domain-containing protein. | 0.639 |
B0511.2 | thoc-2 | B0511.2.1 | C16A3.8.1 | annotation not available | THO Complex (Transcription factor/nuclear export) subunit. | 0.637 |
B0511.2 | xpb-1 | B0511.2.1 | Y66D12A.15.3 | annotation not available | XPB (Xeroderma Pigmentosum complementation group B) related. | 0.943 |
damt-1 | B0511.2 | C18A3.1.1 | B0511.2.1 | DNA N6-methyl methyltransferase; Methylates DNA on the 6th position of adenine (N(6)- methyladenosine). N(6)-methyladenosine (m6A) DNA is involved in epigenetic transgenerational inheritance. Belongs to the MT-A70-like family. | annotation not available | 0.671 |
damt-1 | mett-10 | C18A3.1.1 | ZK1128.2a.1 | DNA N6-methyl methyltransferase; Methylates DNA on the 6th position of adenine (N(6)- methyladenosine). N(6)-methyladenosine (m6A) DNA is involved in epigenetic transgenerational inheritance. Belongs to the MT-A70-like family. | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA) (By similarity). Involved in mRNA splicing (By similarity). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo. Belongs to the methyltransferase superfamily. METTL16/RlmF family. | 0.762 |
damt-1 | mtq-2 | C18A3.1.1 | C33C12.9.1 | DNA N6-methyl methyltransferase; Methylates DNA on the 6th position of adenine (N(6)- methyladenosine). N(6)-methyladenosine (m6A) DNA is involved in epigenetic transgenerational inheritance. Belongs to the MT-A70-like family. | MTS domain-containing protein. | 0.667 |
dyf-5 | B0511.2 | M04C9.5b.1 | B0511.2.1 | Serine/threonine-protein kinase dyf-5; Serine/threonine-protein kinase which is required for ciliogenesis. Regulates the length and the morphology of sensory neuron cilia. In addition, plays a role in the anterograde intraflagellar transport (IFT) in the cilia by regulating the undocking of kinesin-II motor complex (composed of klp-11, klp-20 and kap-1) before reaching the distal segment and the docking of kinesin motor osm-3 onto IFT cargos; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. RCK subfamily. | annotation not available | 0.550 |
eif-3.H | B0511.2 | C41D11.2.1 | B0511.2.1 | Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | annotation not available | 0.697 |
jac-1 | B0511.2 | Y105C5B.21e.1 | B0511.2.1 | Juxtamembrane domain-associated catenin; May act as a positive modulator of hmr-1 function during epidermal morphogenesis. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the beta-catenin family. | annotation not available | 0.637 |
mett-10 | B0511.2 | ZK1128.2a.1 | B0511.2.1 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA) (By similarity). Involved in mRNA splicing (By similarity). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo. Belongs to the methyltransferase superfamily. METTL16/RlmF family. | annotation not available | 0.707 |
mett-10 | damt-1 | ZK1128.2a.1 | C18A3.1.1 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA) (By similarity). Involved in mRNA splicing (By similarity). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo. Belongs to the methyltransferase superfamily. METTL16/RlmF family. | DNA N6-methyl methyltransferase; Methylates DNA on the 6th position of adenine (N(6)- methyladenosine). N(6)-methyladenosine (m6A) DNA is involved in epigenetic transgenerational inheritance. Belongs to the MT-A70-like family. | 0.762 |
mett-10 | thoc-2 | ZK1128.2a.1 | C16A3.8.1 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA) (By similarity). Involved in mRNA splicing (By similarity). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo. Belongs to the methyltransferase superfamily. METTL16/RlmF family. | THO Complex (Transcription factor/nuclear export) subunit. | 0.540 |
mtq-2 | B0511.2 | C33C12.9.1 | B0511.2.1 | MTS domain-containing protein. | annotation not available | 0.552 |