STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0563.6Probable G-protein coupled receptor B0563.6; Not known. Putative receptor; Belongs to the G-protein coupled receptor 1 family. (434 aa)    
Predicted Functional Partners:
npr-18
Neuropeptide receptor 18; Probable receptor for neuropeptide ligand nlp-9 that plays a role in octopamine signaling and specifically, the octapamine inhibition of aversion responses in olfactory sensory neurons. In AWB olfactory sensory neurons, required for the detection of preferred food sources. Belongs to the G-protein coupled receptor 1 family.
   
    0.591
C01F1.4
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
    0.576
kcnl-1
CaMBD domain-containing protein.
   
    0.568
ipp-5
Probable type I inositol 1,4,5-trisphosphate 5-phosphatase; Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
   
    0.564
K08E7.6
Uncharacterized protein.
   
    0.561
sng-1
Synaptogyrin homolog 1; Belongs to the synaptogyrin family.
   
   0.561
ser-5
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
  
    0.560
ggr-1
Glycine receptor subunit beta-type 4; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Contributes to the generation of inhibitory postsynaptic currents.
   
    0.554
T21C9.11
Uncharacterized protein.
   
    0.552
lgc-38
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
    0.551
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.