STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agmo-1Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. (505 aa)    
Predicted Functional Partners:
erg-28
Probable ergosterol biosynthetic protein 28 homolog; Promotes the translocation of slo-1 potassium ion channels from the endoplasmic reticulum to its final destination at the plasma membrane, probably by shielding from premature proteasomal degradation in the endoplasmic reticulum; Belongs to the ERG28 family.
   
 
 0.973
dhcr-7
DeHydroCholesterol Reductase.
   
 0.969
F35C8.5
Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase.
   
 
 0.969
F49E12.10
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.969
drd-1
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.969
W08F4.3
Uncharacterized protein.
   
 0.934
F53B1.4
NAD(P)-bd_dom domain-containing protein.
   
  
 0.923
fath-1
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
   
 
 0.892
C32D5.12
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
  
 0.851
hsd-3
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
  
 0.849
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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