STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C01A2.4Uncharacterized protein. (207 aa)    
Predicted Functional Partners:
did-2
Doa4-Independent Degradation, homologous to yeast Did2.
   
0.968
vps-2
Related to yeast Vacuolar Protein Sorting factor.
   
0.968
vps-4
Related to yeast Vacuolar Protein Sorting factor; Belongs to the AAA ATPase family.
   
 0.959
vps-24
Related to yeast Vacuolar Protein Sorting factor.
   
0.865
vps-32.1
Related to yeast Vacuolar Protein Sorting factor.
   
 0.858
C54D10.10
Uncharacterized protein.
      
 0.851
R12C12.5
Uncharacterized protein.
   
 0.808
pgrn-1
ProGRaNulin homolog.
      
 0.797
istr-1
Increased Sodium Tolerance Related.
   
 0.796
tdp-1
Tar DNA-binding protein homolog 1; RNA-binding protein which regulates transcription, splicing and RNA-editing. Limits the accumulation of double- stranded RNA by maintaining the abundance of the mature RNA transcripts that are formed from double-stranded precursor RNAs. Stress response protein that acts downstream of daf-16 in the insulin/IGF pathway to regulate longevity and the cellular stress response to osmotic, oxidative, proteotoxic and endoplasmic reticulum stress. Involved in the regulation of physiological processes including aging, fertility, growth and locomotion.
      
 0.787
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.