STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nlp-38Neuropeptide-like protein 38; Plays a role in several types of aversive gustatory associative learning including gustatory plasticity and salt avoidance learning. [MIP-1-2]: Neuropeptide ligand for the G-protein coupled receptor sprr-2. (120 aa)    
Predicted Functional Partners:
sprr-2
Sex peptide receptor-related protein 2; G-protein coupled receptor for the neuropeptide like protein nlp-38. Plays a role in several types of aversive gustatory associative learning including gustatory plasticity and salt avoidance learning. Its role in salt avoidance learning may be through activation of the transcription factor crh- 1/CREB and de novo transcription and translation, which in turn promotes the formation of long-term memory.
    
 
 0.792
nlp-71
Neuropeptide-Like Protein.
   
 
 0.778
nlp-59
Neuropeptide-Like Protein.
   
  
 0.767
nlp-67
Neuropeptide-Like Protein.
   
  
 0.765
nlp-17
Neuropeptide-Like Protein.
   
  
 0.714
nlp-69
Neuropeptide-Like Protein.
   
  
 0.704
nlp-19
Neuropeptide-Like Protein.
   
  
 0.701
capa-1
CAPA (Insect neuropeptide) related.
   
  
 0.700
tdpt-1
5'-tyrosyl-DNA phosphodiesterase; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead- end complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals; Belongs to the CCR4/nocturin family. TTRAP/TDP2 subfamily.
      
 0.662
flp-34
FMRF-Like Peptide.
   
  
 0.596
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.