STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hil-7HIstone H1 Like. (66 aa)    
Predicted Functional Partners:
hil-2
Histone H1.2; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
   
  
 0.815
W04A8.4
3'-5' exonuclease domain-containing protein.
   
  
 0.792
hil-3
Histone H1.3; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
   
  
 0.788
F20C5.6
Uncharacterized protein.
   
  
 0.787
clec-196
C-type lectin domain-containing protein.
   
  
 0.719
hil-6
Putative histone H1.6; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
      
 0.699
hil-5
Histone H1.5; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
      
 0.664
ugt-51
UDP-GlucuronosylTransferase.
      
 0.660
ugt-14
UDP-GlucuronosylTransferase.
      
 0.660
lin-59
Probable histone-lysine N-methyltransferase lin-59; Probable histone methyltransferase (By similarity). Essential protein required to maintain expression of homeotic genes egl-5 and mab-5. May play an analogous role to the trithorax Group (trxG) proteins. TrxG proteins form multiprotein complexes that are required to maintain the transcriptionally active state of homeotic genes throughout development. May act via a modification of chromatin.
   
  
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.