STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C01F1.4G_PROTEIN_RECEP_F1_2 domain-containing protein. (333 aa)    
Predicted Functional Partners:
afmd-1
Abhydrolase_3 domain-containing protein.
   
   0.855
par-4
Serine/threonine-protein kinase par-4; Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Controls the asymmetric cell division of the Q.p neuroblast lineage. Involved in mediating cell polarization via regulation of anillin family scaffold proteins. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. May phosphorylate par-1. Required for strd-1 localization to the cell cortex of early embryos and may be required for strd-1 protein s [...]
   
   0.849
B0334.10
Uncharacterized protein.
   
    0.846
srx-39
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
    0.846
str-134
Seven TM Receptor.
   
    0.846
clec-89
C-type LECtin.
   
    0.846
C14E2.6
Lipase_3 domain-containing protein.
   
    0.846
C31H5.1
Uncharacterized protein.
   
    0.846
srt-5
Serpentine Receptor, class T.
   
    0.846
nhr-174
Nuclear hormone receptor family member nhr-174; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
   
    0.846
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.