STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyr-1Putative tyrosinase-like protein tyr-1; Belongs to the tyrosinase family. (601 aa)    
Predicted Functional Partners:
phat-6
PHAryngeal gland Toxin-related.
   
  
 0.756
tyr-6
TYRosinase.
  
  
0.710
ser-5
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.707
C10C5.5
M20_dimer domain-containing protein.
    
 
 0.703
gly-5
Polypeptide N-acetylgalactosaminyltransferase 5; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
      
 0.700
T23B12.8
Putative glycoprotein hormone-beta5.
   
  
 0.698
oac-54
Acyl_transf_3 domain-containing protein.
      
 0.697
tyr-4
TYRosinase.
  
  
0.687
nas-14
Zinc metalloproteinase nas-14; Metalloprotease.
      
 0.679
ipgm-1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
  
 0.678
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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