STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C02D5.4Uncharacterized protein; Belongs to the GST superfamily. (254 aa)    
Predicted Functional Partners:
F22F7.7
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.949
gss-1
Glutathione synthetase.
   
 0.867
gstk-2
Glutathione s-transferase kappa 2; Has roles in respiratory and lipid metabolism.
     
 0.787
gsr-1
Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. Involved in resistance to oxidative stress and starvation. Together with thioredoxin reductase txtr- 1, required for the reduction of disulfide groups in the cuticle during molting.
   
 
 0.781
gstk-1
Glutathione S-transferase kappa 1.
   
 
 0.762
gst-6
Probable glutathione S-transferase 6; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Sigma family.
   
 
 0.759
gst-8
Probable glutathione S-transferase 8; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Sigma family.
   
 
 0.748
gst-1
Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity). Prevents dopaminergic CEP neuron degeneration in response to Mn(2+).
   
 0.745
gst-24
Glutathione S-Transferase.
   
 
 0.735
gst-5
Probable glutathione S-transferase 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity). May play a role in the detoxification of reactive oxygen species produced during pathogenic bacterial infection. Belongs to the GST superfamily. Sigma family.
   
 
 0.733
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.