STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsp-1Tetraspanin-1. (244 aa)    
Predicted Functional Partners:
tsp-2
TetraSPanin family.
   
  
0.893
nas-33
Zinc metalloproteinase nas-33; Metalloprotease.
      
 0.810
fig-1
Uncharacterized protein.
      
 0.759
nas-38
Zinc metalloproteinase nas-38; Metalloprotease.
      
 0.698
nas-31
Zinc metalloproteinase nas-31; Metalloprotease.
      
 0.695
T05B11.1
F-box domain-containing protein.
      
 0.693
nas-16
Zinc metalloproteinase nas-16; Metalloprotease.
      
 0.666
nas-39
Zinc metalloproteinase nas-39; Metalloprotease.
      
 0.663
hch-1
Zinc metalloproteinase nas-34; Metalloprotease (By similarity). Required for normal hatching and migration of neuroblasts. May act by degrading eggshell proteins at hatching.
   
  
 0.663
dpy-31
Zinc metalloproteinase dpy-31; Metalloprotease which cleaves the carboxyl terminus of procollagens, such as sqt-3, to mature collagens (By similarity). Involved in cuticular collagen maturation.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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