STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
npr-19G_PROTEIN_RECEP_F1_2 domain-containing protein. (420 aa)    
Predicted Functional Partners:
npr-32
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.891
nape-1
Lactamase_B domain-containing protein.
      
 0.805
Y53F4B.18
Amidase domain-containing protein.
      
 0.699
faah-1
Fatty acid amide hydrolase 1; Degrades bioactive fatty acid amides like palmitoyl ethanolamide (PEA), palmitoleoyl ethanolamide (POEA), oleoyl ethanolamide (OEA), linoleoyl ethanolamide (LOEA), arachidonoyl ethanolamide (anandamide, or AEA), and eicosapentaneoyl ethanolamide (EPEA), thereby serving to terminate the signaling functions of these molecules. EPEA promotes dauer formation and may constitute a signal of high nutrient availability. Breakdown of EPEA may promote lifespan extension when nutrient availability is high. Facilitates axon regeneration after injury by degradating inh [...]
      
 0.669
faah-4
Monoglyceride lipase faah-4; Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2- arachidonoylglycerol (2-AG), and thereby regulates the degradation of endocannabinoid-related monoacylglycerides. Also hydrolyzes arachidonoyl ethanolamide (anandamide, or AEA), but with low efficiency. Plays a role in the regulation of longevity and resistance to oxidative stress. Belongs to the amidase family.
      
 0.669
npr-14
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.628
T11F9.1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.562
npr-18
Neuropeptide receptor 18; Probable receptor for neuropeptide ligand nlp-9 that plays a role in octopamine signaling and specifically, the octapamine inhibition of aversion responses in olfactory sensory neurons. In AWB olfactory sensory neurons, required for the detection of preferred food sources. Belongs to the G-protein coupled receptor 1 family.
   
  
 0.552
nmur-3
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.544
npr-25
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.542
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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