STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqn-8Prion-like-(Q/N-rich) domain-bearing protein 8. (385 aa)    
Predicted Functional Partners:
B0507.1
EB domain-containing protein.
      
 0.881
Y8A9A.2
Uncharacterized protein.
      
 0.852
phat-3
PHAryngeal gland Toxin-related.
      
 0.811
phat-1
PHAryngeal gland Toxin-related.
      
 0.803
phat-5
PHAryngeal gland Toxin-related.
      
 0.760
phat-6
PHAryngeal gland Toxin-related.
   
  
 0.696
hlh-6
Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity.
      
 0.661
hal-3
Uncharacterized protein hal-3.
      
 0.531
lys-8
LYSozyme.
      
 0.516
nas-14
Zinc metalloproteinase nas-14; Metalloprotease.
      
 0.469
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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