STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C05C9.3Uncharacterized protein. (1436 aa)    
Predicted Functional Partners:
R06C1.4
RRM domain-containing protein.
   
  
 0.971
ash-2
Set1/Ash2 histone methyltransferase complex subunit ash-2; Component of the set-2/ash-2 histone methyltransferase (HMT) complex (Probable). Required for the di- and trimethylation at 'Lys-4' of histone H3, a mark associated with epigenetic transcriptional activation. Implicated in the epigenetic inheritance of lifespan over several generations. Functions as transcriptional regulator. Acts in the germline to limit the longevity of the soma, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturat [...]
    
 
 0.900
nhr-174
Nuclear hormone receptor family member nhr-174; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
   
   0.858
srr-7
Serpentine Receptor, class R.
   
   0.850
F58G11.3
Uncharacterized protein.
   
    0.849
srw-119
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.848
srw-133
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.848
srw-66
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.848
srx-39
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
    0.846
C04B4.6
Ubiquitin-like domain-containing protein.
   
    0.846
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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