STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C05D11.8UPF0518 protein C05D11.8; Belongs to the UPF0518 family. (873 aa)    
Predicted Functional Partners:
ubc-19
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 
 0.777
F22G12.4
Uncharacterized protein.
      
 0.518
C05D11.9
Uncharacterized protein C05D11.9.
 
      0.510
zyg-12
Zygote defective protein 12; Cytoskeletal linker protein, which is essential for attachment of the centrosome to the nucleus. Required for dynein localization to the nuclear envelope. Forms a LINC (LInker of Nucleoskeleton and Cytoskeleton) complex together with unc-84, that may be involved in DNA damage repair ; Belongs to the hook family.
    
 
 0.442
F30A10.9
PINc domain-containing protein.
    
 
 0.410
picc-1
PAC-1 interacting and coiled-coil domain-containing protein 1; Linker protein which helps to recruit the Rho GTPase- activating protein, pac-1, to adherens junctions.
      
 0.408
uri-1
URI (Unconventional prefoldin RPB5 Interactor) homolog.
   
  
 0.406
F35B3.7
Uncharacterized protein.
      
 0.404
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.