node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bas-1 | cat-2 | C05D2.4b.1 | B0432.5a.1 | Biogenic Amine Synthesis related. | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | 0.946 |
bas-1 | got-1.2 | C05D2.4b.1 | T01C8.5.1 | Biogenic Amine Synthesis related. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system. | 0.919 |
bas-1 | got-2.1 | C05D2.4b.1 | C44E4.3.1 | Biogenic Amine Synthesis related. | Aspartate aminotransferase. | 0.912 |
bas-1 | got-2.2 | C05D2.4b.1 | C14F11.1a.2 | Biogenic Amine Synthesis related. | Aspartate aminotransferase. | 0.912 |
bas-1 | pah-1 | C05D2.4b.1 | K08F8.4a.1 | Biogenic Amine Synthesis related. | Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan. Plays a role in the biosynthesis of a melanin-like cuticle pigment. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.958 |
bas-1 | tatn-1 | C05D2.4b.1 | F42D1.2.1 | Biogenic Amine Synthesis related. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.919 |
bas-1 | tbh-1 | C05D2.4b.1 | H13N06.6b.1 | Biogenic Amine Synthesis related. | Tyramine beta-hydroxylase; Required for the conversion of tyramine to octopamine, a precursor of octapamine but probably itself a neurotransmitter. Involved in the regulation of egg laying, which is inhibited by tyramine. Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity. Belongs to the copper type II ascorbate-dependent monooxygenase family. | 0.980 |
bas-1 | tdc-1 | C05D2.4b.1 | K01C8.3b.1 | Biogenic Amine Synthesis related. | Tyrosine decarboxylase; Required for the decarboxylation of tyrosine to tyramine, a precursor of octopamine but probably also itself a neurotransmitter. Involved in the regulation of egg laying, which is inhibited by tyramine. Also involved in controlling locomotion and head movements. Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity which requires octopamine signaling ; Belongs to the group II decarboxylase family. | 0.912 |
bas-1 | tph-1 | C05D2.4b.1 | ZK1290.2a.1 | Biogenic Amine Synthesis related. | BH4_AAA_HYDROXYL_2 domain-containing protein. | 0.993 |
bas-1 | tyr-4 | C05D2.4b.1 | C34G6.2.1 | Biogenic Amine Synthesis related. | TYRosinase. | 0.936 |
cat-2 | bas-1 | B0432.5a.1 | C05D2.4b.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Biogenic Amine Synthesis related. | 0.946 |
cat-2 | got-1.2 | B0432.5a.1 | T01C8.5.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system. | 0.943 |
cat-2 | got-2.1 | B0432.5a.1 | C44E4.3.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Aspartate aminotransferase. | 0.943 |
cat-2 | got-2.2 | B0432.5a.1 | C14F11.1a.2 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Aspartate aminotransferase. | 0.943 |
cat-2 | pah-1 | B0432.5a.1 | K08F8.4a.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Phenylalanine-4-hydroxylase; Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. Catalyzes the hydroxylation of tryptophan to 5-hydroxy-L-tryptophan. Plays a role in the biosynthesis of a melanin-like cuticle pigment. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. | 0.918 |
cat-2 | tatn-1 | B0432.5a.1 | F42D1.2.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. | 0.925 |
cat-2 | tbh-1 | B0432.5a.1 | H13N06.6b.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Tyramine beta-hydroxylase; Required for the conversion of tyramine to octopamine, a precursor of octapamine but probably itself a neurotransmitter. Involved in the regulation of egg laying, which is inhibited by tyramine. Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity. Belongs to the copper type II ascorbate-dependent monooxygenase family. | 0.767 |
cat-2 | tdc-1 | B0432.5a.1 | K01C8.3b.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | Tyrosine decarboxylase; Required for the decarboxylation of tyrosine to tyramine, a precursor of octopamine but probably also itself a neurotransmitter. Involved in the regulation of egg laying, which is inhibited by tyramine. Also involved in controlling locomotion and head movements. Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity which requires octopamine signaling ; Belongs to the group II decarboxylase family. | 0.957 |
cat-2 | tph-1 | B0432.5a.1 | ZK1290.2a.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | BH4_AAA_HYDROXYL_2 domain-containing protein. | 0.923 |
cat-2 | tyr-4 | B0432.5a.1 | C34G6.2.1 | Tyrosine 3-monooxygenase; Involved in the synthesis of catecholamines, such as dopamine. Has a role in serotonin signaling. Required for normal explorative and foraging behavior. | TYRosinase. | 0.913 |