STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C06A1.2Uncharacterized protein. (96 aa)    
Predicted Functional Partners:
F55C12.4
Uncharacterized protein.
   
    0.592
R10E11.5
Uncharacterized protein R10E11.5.
   
    0.592
sng-1
Synaptogyrin homolog 1; Belongs to the synaptogyrin family.
   
    0.592
glrx-5
Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
   
    0.592
tric-1B.1
Trimeric intracellular cation channel type 1B.1; Potassium channel that mediates transmembrane potassium transport. Might be required for maintenance of rapid intracellular calcium release (By similarity). May act as a counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). Binds phosphatidylinositol 4,5- bisphosphate (PIP2).
   
    0.592
afmd-1
Abhydrolase_3 domain-containing protein.
   
    0.588
dyf-5
Serine/threonine-protein kinase dyf-5; Serine/threonine-protein kinase which is required for ciliogenesis. Regulates the length and the morphology of sensory neuron cilia. In addition, plays a role in the anterograde intraflagellar transport (IFT) in the cilia by regulating the undocking of kinesin-II motor complex (composed of klp-11, klp-20 and kap-1) before reaching the distal segment and the docking of kinesin motor osm-3 onto IFT cargos; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. RCK subfamily.
   
    0.588
C31H5.1
Uncharacterized protein.
   
    0.584
ipp-5
Probable type I inositol 1,4,5-trisphosphate 5-phosphatase; Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
   
    0.582
hot-8
Homolog of Odr-2 (Two).
   
    0.578
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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