STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxr-1Thioredoxin reductase 1; Together with glutathione reductase gsr-1, required for the reduction of disulfide groups in the cuticle during molting. (667 aa)    
Predicted Functional Partners:
trx-4
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.972
Y73B6BL.12
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.965
seld-1
Probable selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class I subfamily.
  
 
 0.954
nkat-1
Aminotran_1_2 domain-containing protein.
  
 0.928
nkat-3
Aminotran_1_2 domain-containing protein.
  
 0.928
cth-1
CystaTHionine gamma lyase.
  
 0.918
cth-2
Putative cystathionine gamma-lyase 2; Belongs to the trans-sulfuration enzymes family.
  
 0.918
F13H8.9
Aminotran_5 domain-containing protein.
  
 0.917
trxr-2
Probable glutathione reductase 2; Maintains high levels of reduced glutathione in the cytosol.
  
  
0.911
glrx-21
Glutaredoxin domain-containing protein.
  
 0.899
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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