STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pept-2Peptide transporter family 2; Proton-dependent uptake of di- or tripeptides, and to a minor extent tetrapeptides. Transport is independent of sodium and chloride ions. Protein shows high affinity to peptide substrates. Belongs to the PTR2/POT transporter (TC 2.A.17) family. (785 aa)    
Predicted Functional Partners:
scl-15
SCP domain-containing protein; Belongs to the CRISP family.
  
  
 0.885
C46C11.4
F-box domain-containing protein.
      
 0.806
F39C12.1
Zinc_ribbon_16 domain-containing protein.
      
 0.806
tag-131
Neuferricin homolog; Heme-binding protein.
      
 0.697
nac-1
Sodium-dependent low-affinity dicarboxylate transporter 1; Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
   
  
 0.687
Y19D10A.6
Metalloendopeptidase.
   
  
 0.673
F56C9.11
Uncharacterized protein.
      
 0.661
K04G7.1
Integrase_H2C2 domain-containing protein.
      
 0.661
hira-1
Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.
      
 0.660
mep-1
MOG interacting and ectopic P-granules protein 1; Has a broad role in development, specifically in the genetic pathway SynMuvB that negatively regulates specification of the vulval cell fate. Required for fem-3 3'-UTR-mediated repression in the regulation of the sperm/oocyte switch. Acts by regulating the translation of fem-3 mRNA, by binding to its 3'-UTR.
      
 0.608
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.