STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ncx-7Putative sodium/calcium exchanger 7. (672 aa)    
Predicted Functional Partners:
ncx-2
Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.730
ncx-3
Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.665
ncx-1
Sodium-calcium exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.583
nceh-1
Neutral Cholesterol Ester Hydrolase homolog.
  
  
 0.570
B0454.6
AA_permease_C domain-containing protein.
  
  
 0.552
srsx-34
Serpentine Receptor, class SX.
      
 0.549
nhr-61
Nuclear hormone receptor family member nhr-61; Orphan nuclear receptor.
      
 0.549
mans-3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.544
catp-5
Cation-transporting ATPase catp-5; Involved in the uptake and/or transport of polyamines, probably through ATP hydrolysis. This contributes to the maintenance of intracellular polyamine levels. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
  
 
 0.511
gst-27
Glutathione S-Transferase.
   
  
 0.494
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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