STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pro-2Nucleolar complex protein 2 homolog; Required for normal somatic gonad development and for regulation of germline development and proliferation. (715 aa)    
Predicted Functional Partners:
C37H5.5
Nucleolar complex protein 3 homolog.
   
 
 0.999
F23B12.7
Uncharacterized protein F23B12.7; Belongs to the CBF/MAK21 family.
   
 
 0.999
nst-1
Guanine nucleotide-binding protein-like 3 homolog; May play a role in regulating cellular proliferation in both germline and somatic tissues.
   
 
 0.998
lpd-7
Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.
   
 0.998
nifk-1
RRM domain-containing protein.
   
 
 0.998
Y48B6A.1
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
 0.998
C18A3.3
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA.
   
 0.997
H06I04.3
Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
   
 0.997
nol-2
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.997
let-716
Uncharacterized protein.
   
 
 0.996
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.