node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C48B4.11 | bath-15 | C48B4.11.1 | C08C3.2b.1 | Uncharacterized protein C48B4.11. | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.515 |
bath-15 | C48B4.11 | C08C3.2b.1 | C48B4.11.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Uncharacterized protein C48B4.11. | 0.515 |
bath-15 | bath-4 | C08C3.2b.1 | F52C6.8.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | BTB and MATH domain containing. | 0.541 |
bath-15 | cul-3 | C08C3.2b.1 | Y108G3AL.1a.3 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.475 |
bath-15 | fkh-7 | C08C3.2b.1 | F26D12.1a.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Fork-head domain-containing protein. | 0.702 |
bath-15 | grd-10 | C08C3.2b.1 | F09D12.1.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ground-like domain-containing protein. | 0.535 |
bath-15 | grl-27 | C08C3.2b.1 | F40C5.3.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ground-like domain-containing protein. | 0.612 |
bath-15 | mak-1 | C08C3.2b.1 | K08F8.1a.2 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | MAP kinase-activated protein kinase mak-1; Serine/threonine-protein kinase which may play a role in body wall muscle contraction. May phosphorylate unc-22/twitchin. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.660 |
bath-15 | ttr-33 | C08C3.2b.1 | C37C3.13.2 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | TransThyretin-Related family domain. | 0.660 |
bath-15 | ubc-7 | C08C3.2b.1 | F58A4.10.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Probable ubiquitin-conjugating enzyme E2 7; Catalyzes the covalent attachment of ubiquitin to other proteins. | 0.720 |
bath-15 | uev-3 | C08C3.2b.1 | F26H9.7.1 | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ubiquitin-conjugating enzyme E2 variant 3; Possible negative regulator of polyubiquitination (By similarity). May modulate the activity of the p38 MAP kinase pnk-3. May have a role in axon termination and synaptic transmission at motor and mechanosensory neurons. Plays a role in intraflagellar transport in cilia and cilium length regulation ; Belongs to the ubiquitin-conjugating enzyme family. | 0.705 |
bath-4 | bath-15 | F52C6.8.1 | C08C3.2b.1 | BTB and MATH domain containing. | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.541 |
cul-3 | bath-15 | Y108G3AL.1a.3 | C08C3.2b.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.475 |
cul-3 | ubc-7 | Y108G3AL.1a.3 | F58A4.10.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | Probable ubiquitin-conjugating enzyme E2 7; Catalyzes the covalent attachment of ubiquitin to other proteins. | 0.664 |
cul-3 | uev-3 | Y108G3AL.1a.3 | F26H9.7.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | Ubiquitin-conjugating enzyme E2 variant 3; Possible negative regulator of polyubiquitination (By similarity). May modulate the activity of the p38 MAP kinase pnk-3. May have a role in axon termination and synaptic transmission at motor and mechanosensory neurons. Plays a role in intraflagellar transport in cilia and cilium length regulation ; Belongs to the ubiquitin-conjugating enzyme family. | 0.531 |
fkh-7 | bath-15 | F26D12.1a.1 | C08C3.2b.1 | Fork-head domain-containing protein. | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.702 |
fkh-7 | mak-1 | F26D12.1a.1 | K08F8.1a.2 | Fork-head domain-containing protein. | MAP kinase-activated protein kinase mak-1; Serine/threonine-protein kinase which may play a role in body wall muscle contraction. May phosphorylate unc-22/twitchin. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. | 0.698 |
grd-10 | bath-15 | F09D12.1.1 | C08C3.2b.1 | Ground-like domain-containing protein. | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.535 |
grd-10 | grl-27 | F09D12.1.1 | F40C5.3.1 | Ground-like domain-containing protein. | Ground-like domain-containing protein. | 0.463 |
grl-27 | bath-15 | F40C5.3.1 | C08C3.2b.1 | Ground-like domain-containing protein. | BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.612 |