STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C08F11.12UPF0375 protein C08F11.12. (117 aa)    
Predicted Functional Partners:
C10G8.4
TIL domain-containing protein.
   
    0.999
Y45F10C.2
UPF0375 protein Y45F10C.2; Negatively regulates the egg-laying rate by promoting retention of fertilized eggs.
   
  
0.999
Y62H9A.5
Uncharacterized protein.
   
    0.846
saeg-1
Suppressor of activated egl-4 protein 1; As a likely component of a histone deacetylase complex, together with saeg-2 and hda-2, functions downstream of the cAMP- dependent kinase egl-4 to regulate the expression of genes required for egg-laying and foraging.
      
 0.807
D1054.10
Uncharacterized protein.
   
    0.625
ZK813.2
Uncharacterized protein.
   
    0.618
ule-5
Uterine Lumin Expressed/locailized.
   
    0.592
cht-3
Chitinase-like protein C25A8.4; Putative chitinase; Belongs to the glycosyl hydrolase 18 family.
   
    0.573
ZC373.2
Uncharacterized protein.
   
    0.569
ZK813.1
Uncharacterized protein.
   
    0.551
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.