STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lips-7LIPaSe related. (292 aa)    
Predicted Functional Partners:
ctbp-1
C-terminal-binding protein 1; Binds DNA and represses gene expression. Plays a role in regulation of life span, possibly by regulating transcription of genes important for lipid metabolism.
   
  
 0.810
slo-1
Calcium-activated potassium channel slo-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Essential for the regulation of neurotransmitter release at synapses.
   
  
 0.705
lips-3
LIPaSe related.
   
  
0.604
grl-5
Ground-like domain-containing protein.
   
  
 0.603
Y53F4B.27
Uncharacterized protein.
   
    0.592
T06D8.10
Uncharacterized protein.
   
    0.545
F33A8.7
Uncharacterized protein.
   
    0.541
acdh-6
Probable acyl-CoA dehydrogenase 6; Belongs to the acyl-CoA dehydrogenase family.
   
    0.538
lipl-4
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
      
 0.531
H23N18.5
Uncharacterized protein.
   
    0.516
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.