node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C47G2.3 | ceh-53 | C47G2.3.1 | C09G12.1.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Homeobox domain-containing protein. | 0.614 |
C47G2.3 | sdhd-1 | C47G2.3.1 | F33A8.5.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.895 |
C47G2.3 | tin-10 | C47G2.3.1 | Y66D12A.22.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). | 0.974 |
C47G2.3 | tin-9.1 | C47G2.3.1 | C06G3.11.1 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). Belongs to the small Tim family. | 0.979 |
ceh-53 | C47G2.3 | C09G12.1.1 | C47G2.3.1 | Homeobox domain-containing protein. | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). | 0.614 |
ceh-53 | ceh-79 | C09G12.1.1 | C26E1.3.2 | Homeobox domain-containing protein. | C. Elegans Homeobox. | 0.693 |
ceh-53 | eya-1 | C09G12.1.1 | C49A1.4a.1 | Homeobox domain-containing protein. | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | 0.489 |
ceh-53 | hlh-6 | C09G12.1.1 | T15H9.3.1 | Homeobox domain-containing protein. | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | 0.496 |
ceh-53 | nhr-56 | C09G12.1.1 | F44C8.6a.1 | Homeobox domain-containing protein. | NR LBD domain-containing protein. | 0.817 |
ceh-53 | phat-1 | C09G12.1.1 | C46H11.8.1 | Homeobox domain-containing protein. | PHAryngeal gland Toxin-related. | 0.548 |
ceh-53 | pros-1 | C09G12.1.1 | K12H4.1.1 | Homeobox domain-containing protein. | Homeobox protein prospero homolog 1; Transcription factor involved in developmental processes (By similarity). Controls the transcription of genes required for excretory canal formation. | 0.653 |
ceh-53 | sdhd-1 | C09G12.1.1 | F33A8.5.1 | Homeobox domain-containing protein. | Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.506 |
ceh-53 | tin-10 | C09G12.1.1 | Y66D12A.22.1 | Homeobox domain-containing protein. | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). | 0.496 |
ceh-53 | tin-9.1 | C09G12.1.1 | C06G3.11.1 | Homeobox domain-containing protein. | Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). Belongs to the small Tim family. | 0.604 |
ceh-79 | ceh-53 | C26E1.3.2 | C09G12.1.1 | C. Elegans Homeobox. | Homeobox domain-containing protein. | 0.693 |
eya-1 | ceh-53 | C49A1.4a.1 | C09G12.1.1 | Eyes absent homolog 1; Tyrosine protein phosphatase (By similarity). Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads. Required for the development of anterior tissues during late embryogenesis. Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors. In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die. Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister ce [...] | Homeobox domain-containing protein. | 0.489 |
hlh-6 | ceh-53 | T15H9.3.1 | C09G12.1.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | Homeobox domain-containing protein. | 0.496 |
hlh-6 | nhr-56 | T15H9.3.1 | F44C8.6a.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | NR LBD domain-containing protein. | 0.675 |
hlh-6 | phat-1 | T15H9.3.1 | C46H11.8.1 | Helix-loop-helix protein 6; Transcription factor that regulates the development of the g2 pharyngeal gland cells and pharyngeal gland function and thereby is required for feeding. Required for the expression of a number of genes in the pharyngeal gland, possibly by binding to the E box motif (5'-CANNTG-3') in the promoter region of these genes. Positively regulates the expression of genes encoding mucin-like proteins, which lubricate the pharyngeal tract to ensure efficient passage of the bacterial food source. Exhibits pharyngeal gland-specific positive autoregulation activity. | PHAryngeal gland Toxin-related. | 0.853 |
nhr-56 | ceh-53 | F44C8.6a.1 | C09G12.1.1 | NR LBD domain-containing protein. | Homeobox domain-containing protein. | 0.817 |