STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bli-1Cuticle collagen bli-1; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment. This collagen is required for proper strut formation within the unique medial layer of the adult cuticle. (948 aa)    
Predicted Functional Partners:
bli-2
Col_cuticle_N domain-containing protein.
   
  
0.904
E01G4.6
Uncharacterized protein.
   
    0.846
mlt-7
Peroxidase mlt-7 heavy chain; Plays an essential role in cuticle biogenesis. Required in combination with bli-3 for correct formation of cross-links in cuticle collagens.
      
 0.695
F14F7.5
WSN domain-containing protein.
   
 
 0.685
Y43F8B.9
Uncharacterized protein.
      
 0.660
oac-30
Acyl_transf_3 domain-containing protein.
   
 
 0.651
rol-1
Col_cuticle_N domain-containing protein.
   
  
0.635
dao-4
Dauer or Aging adult Overexpression.
   
  
 0.630
col-138
Col_cuticle_N domain-containing protein.
   
  
0.621
col-175
Col_cuticle_N domain-containing protein.
   
   
0.596
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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