Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdap-2 | spr-4 | Y44E3A.4.1 | C09H6.1a.1 | CD2AP homolog. | Suppressor of presenilin protein 4; Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1. Might play a role in the oxidative stress response. | 0.544 |
| gon-14 | lsy-2 | F44C4.4a.1 | F49H12.1a.1 | Dimer_Tnp_hAT domain-containing protein. | Uncharacterized protein. | 0.696 |
| gon-14 | mcd-1 | F44C4.4a.1 | Y51H1A.6a.1 | Dimer_Tnp_hAT domain-containing protein. | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | 0.693 |
| gon-14 | spr-4 | F44C4.4a.1 | C09H6.1a.1 | Dimer_Tnp_hAT domain-containing protein. | Suppressor of presenilin protein 4; Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1. Might play a role in the oxidative stress response. | 0.481 |
| gon-14 | zfp-2 | F44C4.4a.1 | F35H8.3.1 | Dimer_Tnp_hAT domain-containing protein. | Zinc finger protein zfp-2; Probable zinc finger transcription factor that acts as a transcriptional repressor. Acts redundantly with the transcriptional repressor lin-35 to control the development of somatic gonad lineages. May, in addition, suppress sensitivity to RNAi. | 0.779 |
| hop-1 | sel-12 | C18E3.8.1 | F35H12.3.1 | Presenilin hop-1; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Probably works redundantly of lin-12, which provides more presenilin function. | Presenilin sel-12; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Provides the major presenilin function compared to hop-1 and spe-4. Required cell-autonomously for correct neurite connectivity of the AIY cholinergic interneurons and their correct functioning in thermotaxis. Required for mesodermal patterning of muscle function. Promotes basement membrane gap formation during tissue remodeling ; Belongs to the peptidase A22A family. | 0.923 |
| hop-1 | spr-1 | C18E3.8.1 | D1014.8.1 | Presenilin hop-1; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Probably works redundantly of lin-12, which provides more presenilin function. | REST corepressor spr-1; Probable corepressor protein, which probably participates in the transcriptional repression of the presenilin protein hop-1. Probably acts via the formation of a multiprotein complex that deacetylates and demethylates specific sites on histones. Acts redundantly with the transcriptional repressor lin-35 to play a role in vulval morphogenesis and promote germline proliferation ; Belongs to the CoREST family. | 0.669 |
| hop-1 | spr-2 | C18E3.8.1 | C27B7.1b.1 | Presenilin hop-1; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Probably works redundantly of lin-12, which provides more presenilin function. | Suppressor of presenilin-2; Potential corepressor protein, which may affect chromatin structure and/or transcription. May participate in the transcriptional repression of the presenilin protein hop-1. Belongs to the nucleosome assembly protein (NAP) family. | 0.422 |
| hop-1 | spr-4 | C18E3.8.1 | C09H6.1a.1 | Presenilin hop-1; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Probably works redundantly of lin-12, which provides more presenilin function. | Suppressor of presenilin protein 4; Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1. Might play a role in the oxidative stress response. | 0.614 |
| lsy-2 | gon-14 | F49H12.1a.1 | F44C4.4a.1 | Uncharacterized protein. | Dimer_Tnp_hAT domain-containing protein. | 0.696 |
| lsy-2 | mcd-1 | F49H12.1a.1 | Y51H1A.6a.1 | Uncharacterized protein. | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | 0.679 |
| lsy-2 | spr-4 | F49H12.1a.1 | C09H6.1a.1 | Uncharacterized protein. | Suppressor of presenilin protein 4; Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1. Might play a role in the oxidative stress response. | 0.452 |
| mcd-1 | gon-14 | Y51H1A.6a.1 | F44C4.4a.1 | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | Dimer_Tnp_hAT domain-containing protein. | 0.693 |
| mcd-1 | lsy-2 | Y51H1A.6a.1 | F49H12.1a.1 | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | Uncharacterized protein. | 0.679 |
| mcd-1 | spr-4 | Y51H1A.6a.1 | C09H6.1a.1 | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | Suppressor of presenilin protein 4; Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1. Might play a role in the oxidative stress response. | 0.548 |
| mcd-1 | spr-5 | Y51H1A.6a.1 | Y40B1B.6.1 | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3 (By similarity). Participates in the transcriptional repression of the presenilin protein hop-1. May act via the formation of a multiprotein complex that remodel or modify the chromatin. Together wi [...] | 0.415 |
| mcd-1 | zfp-2 | Y51H1A.6a.1 | F35H8.3.1 | Modifier of cell death; Promotes programmed cell death. Its role in programmed cell death may be in conjunction with cell cycle regulatory factor efl-1 and the synthetic multivulva class B proteins dpl-1 and lin-35, and is independent of the ced-1, ced-8 and ced-9 pathways. | Zinc finger protein zfp-2; Probable zinc finger transcription factor that acts as a transcriptional repressor. Acts redundantly with the transcriptional repressor lin-35 to control the development of somatic gonad lineages. May, in addition, suppress sensitivity to RNAi. | 0.702 |
| sel-12 | hop-1 | F35H12.3.1 | C18E3.8.1 | Presenilin sel-12; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Provides the major presenilin function compared to hop-1 and spe-4. Required cell-autonomously for correct neurite connectivity of the AIY cholinergic interneurons and their correct functioning in thermotaxis. Required for mesodermal patterning of muscle function. Promotes basement membrane gap formation during tissue remodeling ; Belongs to the peptidase A22A family. | Presenilin hop-1; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Probably works redundantly of lin-12, which provides more presenilin function. | 0.923 |
| sel-12 | spr-1 | F35H12.3.1 | D1014.8.1 | Presenilin sel-12; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Provides the major presenilin function compared to hop-1 and spe-4. Required cell-autonomously for correct neurite connectivity of the AIY cholinergic interneurons and their correct functioning in thermotaxis. Required for mesodermal patterning of muscle function. Promotes basement membrane gap formation during tissue remodeling ; Belongs to the peptidase A22A family. | REST corepressor spr-1; Probable corepressor protein, which probably participates in the transcriptional repression of the presenilin protein hop-1. Probably acts via the formation of a multiprotein complex that deacetylates and demethylates specific sites on histones. Acts redundantly with the transcriptional repressor lin-35 to play a role in vulval morphogenesis and promote germline proliferation ; Belongs to the CoREST family. | 0.691 |
| sel-12 | spr-4 | F35H12.3.1 | C09H6.1a.1 | Presenilin sel-12; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Provides the major presenilin function compared to hop-1 and spe-4. Required cell-autonomously for correct neurite connectivity of the AIY cholinergic interneurons and their correct functioning in thermotaxis. Required for mesodermal patterning of muscle function. Promotes basement membrane gap formation during tissue remodeling ; Belongs to the peptidase A22A family. | Suppressor of presenilin protein 4; Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1. Might play a role in the oxidative stress response. | 0.700 |
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