node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbd-1 | chs-1 | H02I12.1.1 | T25G3.2.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | 0.920 |
cbd-1 | clec-88 | H02I12.1.1 | K10B2.3b.2 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | C-type lectin domain-containing protein 88. | 0.554 |
cbd-1 | cpg-2 | H02I12.1.1 | B0280.5.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Chondroitin proteoglycan-2; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | 0.897 |
cbd-1 | cpg-3 | H02I12.1.1 | R06C7.4.3 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Chondroitin proteoglycan 3. | 0.999 |
cbd-1 | cpg-4 | H02I12.1.1 | C10F3.1.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Chondroitin proteoglycan 4. | 0.762 |
cbd-1 | egg-5 | H02I12.1.1 | R12E2.10.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Inactive protein-tyrosine phosphatase egg-5; Inactive phosphatase which acts redundantly with egg-4 in the oocyte-to-zygote transition. Required for polarized cortical actin cytoskeleton rearrangement in the oocyte before and after fertilization. Together with egg-4, required for the cortical localization of kinase mbk-2 in maturing oocyte until the end of meiosis I. Also required for kinase mbk-2, pseudophosphatase egg-3 and chitin synthase chs-1 localization to cytoplasmic foci after fertilization. | 0.999 |
cbd-1 | gna-2 | H02I12.1.1 | T23G11.2.1 | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | 0.693 |
chs-1 | cbd-1 | T25G3.2.1 | H02I12.1.1 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | 0.920 |
chs-1 | cpg-2 | T25G3.2.1 | B0280.5.1 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | Chondroitin proteoglycan-2; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | 0.859 |
chs-1 | cpg-3 | T25G3.2.1 | R06C7.4.3 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | Chondroitin proteoglycan 3. | 0.728 |
chs-1 | cpg-4 | T25G3.2.1 | C10F3.1.1 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | Chondroitin proteoglycan 4. | 0.700 |
chs-1 | egg-5 | T25G3.2.1 | R12E2.10.1 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | Inactive protein-tyrosine phosphatase egg-5; Inactive phosphatase which acts redundantly with egg-4 in the oocyte-to-zygote transition. Required for polarized cortical actin cytoskeleton rearrangement in the oocyte before and after fertilization. Together with egg-4, required for the cortical localization of kinase mbk-2 in maturing oocyte until the end of meiosis I. Also required for kinase mbk-2, pseudophosphatase egg-3 and chitin synthase chs-1 localization to cytoplasmic foci after fertilization. | 0.880 |
chs-1 | gna-2 | T25G3.2.1 | T23G11.2.1 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. | 0.752 |
chs-1 | har-2 | T25G3.2.1 | T24D1.5.1 | Chitin synthase chs-1; Essential for the embryonic synthesis of chitin, a component of the eggshell. | RING-type domain-containing protein. | 0.400 |
clec-88 | cbd-1 | K10B2.3b.2 | H02I12.1.1 | C-type lectin domain-containing protein 88. | Chitin-binding domain protein cbd-1; In unfertilized oocytes, maintains egg-1 and egg-2 at the plasma membrane together with chitin synthase chs-1 and kinase mbk-2. Essential for the formation of a continuous and cohesive chitin layer following fertilization. | 0.554 |
clec-88 | cpg-2 | K10B2.3b.2 | B0280.5.1 | C-type lectin domain-containing protein 88. | Chondroitin proteoglycan-2; Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Has roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin. | 0.636 |
clec-88 | cpg-3 | K10B2.3b.2 | R06C7.4.3 | C-type lectin domain-containing protein 88. | Chondroitin proteoglycan 3. | 0.996 |
clec-88 | cpg-4 | K10B2.3b.2 | C10F3.1.1 | C-type lectin domain-containing protein 88. | Chondroitin proteoglycan 4. | 0.759 |
clec-88 | cpg-8 | K10B2.3b.2 | K03B4.7a.1 | C-type lectin domain-containing protein 88. | Chondroitin proteoglycan 8. | 0.892 |
clec-88 | egg-5 | K10B2.3b.2 | R12E2.10.1 | C-type lectin domain-containing protein 88. | Inactive protein-tyrosine phosphatase egg-5; Inactive phosphatase which acts redundantly with egg-4 in the oocyte-to-zygote transition. Required for polarized cortical actin cytoskeleton rearrangement in the oocyte before and after fertilization. Together with egg-4, required for the cortical localization of kinase mbk-2 in maturing oocyte until the end of meiosis I. Also required for kinase mbk-2, pseudophosphatase egg-3 and chitin synthase chs-1 localization to cytoplasmic foci after fertilization. | 0.557 |