node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F26A10.2 | sox-4 | F26A10.2.1 | C12D12.5b.1 | Uncharacterized protein. | HMG box domain-containing protein. | 0.494 |
egl-13 | hmp-2 | T22B7.1a.1 | K05C4.6b.1 | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | 0.633 |
egl-13 | pop-1 | T22B7.1a.1 | W10C8.2.1 | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | 0.544 |
egl-13 | sem-2 | T22B7.1a.1 | C32E12.5.2 | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | Transcription factor sem-2; Probable transcription factor required for embryogenesis, vulval development and cell fate specification of the postembryonic mesoderm (also known as the M lineage). Specifically, required for the specification of sex myoblast cells and their development into the muscles that are necessary for egg-laying. In addition, may be involved in RME GABAergic motor neuron progenitor cell fate specification. | 0.607 |
egl-13 | sox-2 | T22B7.1a.1 | K08A8.2a.2 | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | Transcription factor sox-2; Probable transcription factor that regulates the lineage progression of embryonic blast cells and controls the postmitotic specification and differentiation of neurons. Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor ceh-36 to specify AWC neurons and with the LIM homeodomain factor lim-4 to suppress AWC terminal differentiation and promote AWB neuron differentiation. Plays a role in the terminal differentiation of glutamatergic and cholinergic neurons. Required for natural r [...] | 0.643 |
egl-13 | sox-3 | T22B7.1a.1 | F40E10.2.1 | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | HMG box domain-containing protein. | 0.620 |
egl-13 | sox-4 | T22B7.1a.1 | C12D12.5b.1 | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | HMG box domain-containing protein. | 0.625 |
fut-2 | sox-4 | EGAP9.2.1 | C12D12.5b.1 | Galactoside 2-alpha-L-fucosyltransferase; Selectively catalyzes the addition of fucose in alpha 1-2 linkage to Gal-beta-(1->4)-Xyl-beta-R, Gal-beta-(1->6)-GlcNAc-R, Gal- beta-(1->3)-Gal-beta-(1->4)-Glc and Gal-beta-(1->3)-Gal-beta-(1->4)- Xyl-R acceptors but not Gal-beta-(1->3)-GlcNAc-beta-(1->3)-Gal-beta- (1->4)-Glc. Unlike in mammals, unable to fucosylate Gal-beta-(1->4)- Glc-beta-R. | HMG box domain-containing protein. | 0.694 |
hmp-2 | egl-13 | K05C4.6b.1 | T22B7.1a.1 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | 0.633 |
hmp-2 | pop-1 | K05C4.6b.1 | W10C8.2.1 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | 0.996 |
hmp-2 | sem-2 | K05C4.6b.1 | C32E12.5.2 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | Transcription factor sem-2; Probable transcription factor required for embryogenesis, vulval development and cell fate specification of the postembryonic mesoderm (also known as the M lineage). Specifically, required for the specification of sex myoblast cells and their development into the muscles that are necessary for egg-laying. In addition, may be involved in RME GABAergic motor neuron progenitor cell fate specification. | 0.598 |
hmp-2 | sox-2 | K05C4.6b.1 | K08A8.2a.2 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | Transcription factor sox-2; Probable transcription factor that regulates the lineage progression of embryonic blast cells and controls the postmitotic specification and differentiation of neurons. Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor ceh-36 to specify AWC neurons and with the LIM homeodomain factor lim-4 to suppress AWC terminal differentiation and promote AWB neuron differentiation. Plays a role in the terminal differentiation of glutamatergic and cholinergic neurons. Required for natural r [...] | 0.610 |
hmp-2 | sox-3 | K05C4.6b.1 | F40E10.2.1 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | HMG box domain-containing protein. | 0.607 |
hmp-2 | sox-4 | K05C4.6b.1 | C12D12.5b.1 | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | HMG box domain-containing protein. | 0.607 |
irx-1 | sox-2 | C36F7.1.1 | K08A8.2a.2 | Putative iroquois-class homeodomain protein irx-1. | Transcription factor sox-2; Probable transcription factor that regulates the lineage progression of embryonic blast cells and controls the postmitotic specification and differentiation of neurons. Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor ceh-36 to specify AWC neurons and with the LIM homeodomain factor lim-4 to suppress AWC terminal differentiation and promote AWB neuron differentiation. Plays a role in the terminal differentiation of glutamatergic and cholinergic neurons. Required for natural r [...] | 0.513 |
irx-1 | sox-3 | C36F7.1.1 | F40E10.2.1 | Putative iroquois-class homeodomain protein irx-1. | HMG box domain-containing protein. | 0.778 |
irx-1 | sox-4 | C36F7.1.1 | C12D12.5b.1 | Putative iroquois-class homeodomain protein irx-1. | HMG box domain-containing protein. | 0.762 |
pop-1 | egl-13 | W10C8.2.1 | T22B7.1a.1 | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | Transcription factor egl-13; Probable transcription factor that is required for uterine cell fate decisions. Controls genes required for the specification and differentiation of O(2) and CO(2)- sensing neurons and for maintaining URX sensory neuronal cell fate. | 0.544 |
pop-1 | hmp-2 | W10C8.2.1 | K05C4.6b.1 | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | Beta-catenin-like protein hmp-2; Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions. | 0.996 |
pop-1 | sem-2 | W10C8.2.1 | C32E12.5.2 | Protein pop-1; Part of the Wnt signaling pathway essential for the specification of the mesodermal cell fate in early embryos. Required for asymmetrical division of somatic gonadal precursor descendants which initiate axis formation required to control organ shape. Represses expression of target genes via its interaction with hda-1 histone deacetylase. Required for specification of the M lineage-derived coelomocyte and sex myoblast fate. Regulates coelomocyte fate by positively regulating proliferation and ceh-34 and possibly eya-1 expression in M.dlpa and M.drpa precursors. | Transcription factor sem-2; Probable transcription factor required for embryogenesis, vulval development and cell fate specification of the postembryonic mesoderm (also known as the M lineage). Specifically, required for the specification of sex myoblast cells and their development into the muscles that are necessary for egg-laying. In addition, may be involved in RME GABAergic motor neuron progenitor cell fate specification. | 0.635 |