STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rop-160 kDa SS-A/Ro ribonucleoprotein homolog; RNA-binding protein that binds to a single small cytoplasmic RNA molecule known as Y RNA. May stabilize this RNA from degradation; Belongs to the Ro 60 kDa family. (643 aa)    
Predicted Functional Partners:
ssb-1
Sjogren Syndrome antigen B homolog.
   
 
 0.762
C11D2.7
PUA domain-containing protein.
      
 0.759
C15C6.4
Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
      
 0.759
T03G11.3
Zinc finger C2HC domain-containing protein T03G11.3; Belongs to the ZC2HC1 family.
      
 0.751
Y82E9BR.19
F-box domain-containing protein.
      
 0.751
xpo-3
Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.
   
  
 0.726
R11H6.5
Uncharacterized protein.
    
 
 0.725
F08B4.7
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
      
 0.724
larp-5
HTH La-type RNA-binding domain-containing protein.
   
  
 0.704
D2005.1
A to I editase domain-containing protein.
      
 0.702
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.