STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ssr-2Sperm-Specific family, class R. (320 aa)    
Predicted Functional Partners:
shn-1
Protein shank; Scaffold protein that most likely acts in the postsynaptic density (PSD) of excitatory synapses which orchestrates synapse formation and maintenance at neuromuscular junctions. Associates with and trafficks the L-type calcium channel egl-19 to the cell surface of body wall muscles to ensure the function of the calcium channel and therefore maintain the Ca(2+) current density. The maintenance of Ca(2+) also allows for the downstream regulation of Ca(2+)-induced expression of genes such as gem-4. Plays a role in the regulation of the defecation cycle, and this may be in as [...]
  
 
 0.870
src-2
Tyrosine protein-kinase src-2; Non-receptor tyrosine-protein kinase which may play a role in larval and pharynx development. Unlike src-1, does not play a role in embryonic development.
   
 
 0.736
C56E6.2
Uncharacterized protein.
  
 
 
 0.733
T04C9.1
Uncharacterized protein.
    
 
 0.712
C52B11.5
Uncharacterized protein.
   
 
 0.711
mtcu-1
TrmE-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
 
 0.680
efsc-1
Tr-type G domain-containing protein.
      
 0.665
exoc-7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
    
 
 0.654
K02E10.1
Uncharacterized protein.
  
 
 0.636
F11A5.4
Uncharacterized protein.
      
 0.613
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.