STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C14B1.3Uncharacterized protein. (384 aa)    
Predicted Functional Partners:
skr-1
Skp1-related protein; Probable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates cell proliferation during embryonic and larval development. Involved in synapse elimination in early synapse development. May negatively regulate the apoptotic activity of cep-1 in response to genotoxic stress. Plays a role in sex determination.
   
 0.889
C40H1.2
Uncharacterized protein C40H1.2.
   
  
 0.811
F33G12.6
PPM-type phosphatase domain-containing protein.
      
 0.810
F46F5.11
Uncharacterized protein.
      
 0.810
R10F2.6
Tyrosine-protein phosphatase domain-containing protein.
      
 0.810
ZC84.6
Uncharacterized protein.
      
 0.807
upb-1
CN hydrolase domain-containing protein.
      
 0.759
ZK1307.8
Uncharacterized protein.
      
 0.759
skr-2
SKp1 Related (Ubiquitin ligase complex component).
    
 
 0.752
F23F12.3
Uncharacterized protein F23F12.3.
      
 0.741
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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