STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ril-2RNAi-Induced Longevity. (677 aa)    
Predicted Functional Partners:
Y82E9BR.16
MFS domain-containing protein.
    
 
 0.815
rha-2
Putative ATP-dependent RNA helicase rha-2; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily.
   
 
 0.793
ril-1
RNAi-Induced Longevity.
   
  
 0.759
C34C12.8
GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
   
  
 0.750
gip-1
Gamma-tubulin complex component.
   
 
 0.742
drr-1
MARVEL domain-containing protein.
      
 0.695
C16A3.5
Uncharacterized protein; Belongs to the complex I LYR family.
      
 0.690
F02A9.10
Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family.
   
 
 0.631
pccb-1
Propionyl Coenzyme A Carboxylase Beta subunit.
   
 
 0.631
pcn-1
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
   0.629
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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