STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrch-1Calponin-homology (CH) domain-containing protein. (638 aa)    
Predicted Functional Partners:
klf-2
Kruppel-Like Factor (Zinc finger protein).
    
 
 0.765
rbm-22
RNA Binding Motif protein homolog.
    
 
 0.680
lat-1
Latrophilin-like protein 1; Has a role in the establishment of anterior-posterior polarity in tissues during embryogenesis. Required for the alignment of the mitotic spindles and division planes. May have a role in cell death events. Required for normal defection and oocyte fertilization. Involved in sperm function. Operates in pharyngeal pumping during feeding. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
   
   0.637
F44A2.5
MIF4G domain-containing protein.
   
  
 0.614
peli-1
PELI1 and PELI2 related.
   
  
 0.548
lron-9
ELRR (Extracellular Leucine-Rich Repeat) ONly.
  
   0.534
rab-5
RAB family.
    
 
 0.531
lron-1
LRRCT domain-containing protein.
  
   0.517
dma-1
LRRCT domain-containing protein.
  
 
 0.516
phlp-2
Protein phosphatase PHLPP-like protein; Probable protein phosphatase.
  
 
   0.498
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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