STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cky-1BHLH-PAS factor. (676 aa)    
Predicted Functional Partners:
aha-1
Aryl hydrocarbon receptor nuclear translocator homolog; Has a role in cellular differentiation. Required for pharyngeal development. In collaboration with ahr-1 it is involved in RMEL/R and SDQR neuron cell migration. Acts in the cellular response to hypoxia. Involved in aggregation behavior by regulating soluble guanylate cyclase gene expression in the URX neurons.
    
 0.999
nhr-127
Nuclear hormone receptor family member nhr-127; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
   
  
 0.853
hlh-34
Helix-loop-helix 34; Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development (By similarity).
   
  
 0.816
nhr-99
Nuclear Hormone Receptor family.
      
 0.807
nhr-19
Nuclear hormone receptor family member nhr-19; Orphan nuclear receptor.
      
 0.806
peb-1
FLYWCH-type domain-containing protein.
   
  
 0.706
Y23H5B.5
WD_REPEATS_REGION domain-containing protein.
   
    0.701
nhr-116
Nuclear Hormone Receptor family.
      
 0.699
Y54E5B.2
WD_REPEATS_REGION domain-containing protein.
   
    0.697
M28.5
NHP2-like protein 1 homolog; Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding (By similarity); Belongs to the eukaryotic ribosomal protein eL8 family.
   
    0.681
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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