STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrg-7Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (428 aa)    
Predicted Functional Partners:
R193.2
Uncharacterized protein.
   
  
 0.881
srv-3
Serpentine receptor class gamma; Belongs to the nematode receptor-like protein srg family.
      
 0.805
hrg-4
Heme transporter hrg-4; Heme transporter that mediates heme uptake across the plasma membrane; Belongs to the HRG family.
   
  
 0.792
hrg-5
Heme transporter hrg-5; Heme transporter.
      
 0.741
clec-5
C-type LECtin.
   
  
 0.708
glb-10
GLOBIN domain-containing protein; Belongs to the globin family.
    
 
 0.702
clec-60
VWFA domain-containing protein.
    
 
 0.698
cpr-5
Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family.
   
 
 0.683
hrg-3
Heme Responsive protein.
   
  
 0.670
cpr-1
Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family.
   
 0.667
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]