STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C15C8.4Putative low density lipoprotein receptor associated protein (37.4 kD). (316 aa)    
Predicted Functional Partners:
C34C12.4
Uncharacterized protein C34C12.4.
      
 0.920
W09G3.7
Uncharacterized protein.
      
 0.915
F09G2.2
Cyclin N-terminal domain-containing protein.
      
 0.912
maco-1
Macoilin; Plays a role in the regulation of neuronal activity.
   
  
 0.810
lrp-1
Low-density lipoprotein receptor-related protein; May act as a receptor for the endocytosis of extracellular ligands such as chylomicron remnants, protease-inhibitor complexes and vitellogenin; Belongs to the LDLR family.
    
 
 0.714
Y66D12A.10
MIT_C domain-containing protein.
   
  
 0.708
epac-1
Rap guanine nucleotide exchange factor 1; Guanine nucleotide-releasing protein (By similarity). Together with GTPase drn-1, may regulate acetylcholine release at the neuromuscular junctions probably downstream of G-protein gsa-1 and adenylate cyclase acy-1.
      
 0.575
atrn-1
Putative protein tag-53.
      
 0.539
coel-1
Tubulin folding COfactor E-Like protein.
      
 0.466
ddl-3
Daf-16-Dependent Longevity (WT but not daf-16 lifespan increased).
   
  
 0.428
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.