STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C16C10.1Uncharacterized mitochondrial carrier C16C10.1. (360 aa)    
Predicted Functional Partners:
lars-1
Leucine--tRNA ligase; Involved in protein synthesis. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
 
      0.629
txl-1
Thioredoxin-like protein TXL.
   
    0.585
Y39B6A.3
Fe-S_biosyn domain-containing protein.
   
  
 0.553
Y55F3AR.2
Thioredoxin domain-containing protein.
   
    0.507
abtm-1
ABC Transporter, Mitochondrial.
      
 0.483
mfn-1
Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
0.432
mtm-6
Myotubularin-related protein 6; May dephosphorylate phosphatidylinositol-3-phosphate (PI3P). In association with mtm-9, plays a role in endosome trafficking probably by regulating phosphatidylinositol-3-phosphate levels. Regulates fluid phase endocytosis in coelomocytes. Controls the endosomal localization of sorting nexin snx-3 and the levels of sorting receptor mig-14. By regulating the retrograde transport of mig-14, may be involved in the secretion of Wnt ligands such as egl-20. Regulates posterior migration of QL neuroblast descendants and the anterior migration of QR neuroblast d [...]
   
  
 0.430
mspn-1
Mitochondrial sorting homolog; Involved in intramitochondrial sorting of proteins.
   
    0.425
F39H2.3
GCV_T domain-containing protein.
   
  
 0.415
tbc-12
Rab-GAP TBC domain-containing protein.
      
 0.408
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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