STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
inx-1Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (428 aa)    
Predicted Functional Partners:
gcy-13
Receptor-type guanylate cyclase gcy-13; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
      
 0.812
unc-1
Protein unc-1.
   
  
 0.643
flp-26
FMRFamide-like neuropeptides 26; FMRFamides and FMRFamide-like peptides are neuropeptides.
   
  
 0.564
egl-19
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
 0.480
cex-1
Calexcitin-1.
    
 
 0.452
eat-4
Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior.
   
 
 0.450
srh-18
Serpentine Receptor, class H.
      
 0.428
F32B5.7
Uncharacterized protein.
  
   0.424
lgc-49
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.418
dmsr-5
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
    0.418
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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