STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-124Nuclear hormone receptor family member nhr-124; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. (377 aa)    
Predicted Functional Partners:
nhr-81
Nuclear Hormone Receptor family.
  
    0.678
nhr-234
Nuclear Hormone Receptor family; Belongs to the nuclear hormone receptor family.
  
    0.673
nhr-169
Nuclear hormone receptor family member nhr-169; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
  
    0.666
nhr-174
Nuclear hormone receptor family member nhr-174; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
  
    0.628
irld-29
Recep_L_domain domain-containing protein.
   
    0.565
C16D9.8
Uncharacterized protein.
   
    0.542
ceh-6
Homeobox protein ceh-6; Vital for embryonic development and essential for the proper function of the excretory cell. Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development.
  
   0.539
C14E2.6
Lipase_3 domain-containing protein.
   
    0.532
srt-58
Nuclear receptor domain-containing protein.
  
    0.532
dpr-1
Dauer Pheromone Responsive.
  
    0.530
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.