STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tiar-1RRM domain-containing protein. (408 aa)    
Predicted Functional Partners:
gtbp-1
Ras-Gtpase-activating protein SH3 (Three) domain-Binding Protein.
   
 
 0.856
cgh-1
ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
  
 
 0.771
dcap-2
mRNA-decapping enzyme 2; RNA-decapping enzyme although it does not bind cap. May contribute to gene regulation in multiple RNA pathways including monomethylguanosine- and trimethylguanosine-capped RNAs. Belongs to the Nudix hydrolase family. DCP2 subfamily.
   
  
 0.748
C06A6.2
Uncharacterized protein.
   
  
 0.745
stau-1
STAUfen (DsRNA binding protein) homolog.
   
 
 0.707
dcap-1
mRNA_decap_C domain-containing protein.
   
 
 0.693
vbh-1
Vasa-and Belle-like Helicase; Belongs to the DEAD box helicase family.
  
 
 0.679
pqn-59
Prion-like-(Q/N-rich)-domain-bearing protein.
   
 
 0.663
Y17G7B.18
Probable RNA methyltransferase Y17G7B.18; Probable RNA methyltransferase; Belongs to the methyltransferase superfamily.
   
 
 0.661
F25B5.3
Putative cytosolic 5'-nucleotidase 3.
   
  
 0.631
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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