STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
seb-3Secretin receptor-like protein SEB-3; Belongs to the G-protein coupled receptor 2 family. (454 aa)    
Predicted Functional Partners:
gsa-1
G protein, Subunit Alpha.
   
 
 0.874
crf-1
Neuropeptide-Like Protein.
   
 
 0.873
egl-30
Heterotrimeric G protein alpha subunit.
    
 
 0.860
gpb-2
Guanine nucleotide-binding protein subunit beta-2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
   0.854
gpb-1
Guanine nucleotide-binding protein subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. In the early embryo, controls the magnitude of the forces acting on centrosomes but is not required for generating asymmetric forces.
   
   0.851
Y25C1A.7
Yip1 domain-containing protein.
      
 0.699
znf-207
BED-type domain-containing protein.
      
 0.692
C01F1.4
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.666
tkr-3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
  
 0.654
frpr-19
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.630
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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