STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C18B12.4RING-type domain-containing protein. (456 aa)    
Predicted Functional Partners:
F17B5.6
Uncharacterized protein.
   
  
 0.894
mnp-1
Matrix non-peptidase homolog 1.
      
 0.850
C27C7.5
Galectin.
    
 
 0.678
C04F12.7
Uncharacterized protein.
      
 0.660
oac-9
NRF domain-containing protein.
      
 0.660
slc-25A42
SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.660
ZC190.5
Uncharacterized protein.
      
 0.660
mans-1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.621
B0041.5
Uncharacterized protein.
      
 0.614
ptp-3
Tyrosine-protein phosphatase Lar-like; Has a role in early neural and epidermal development; neuroblast movements during closure of the gastrulation cleft and epidermal morphogenesis. Vab-1 and ptp-3 may function redundantly within the same sets of neuronal precursors.
   
  
 0.575
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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