STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
die-1C2H2-type domain-containing protein. (646 aa)    
Predicted Functional Partners:
cog-1
Homeobox domain-containing protein.
    
 
 0.805
lsy-2
Uncharacterized protein.
   
 
 0.770
fozi-1
Formin-homology and zinc finger domains protein 1; Acts redundantly with hlh-1 to promote body wall muscle cell and coelomocyte specification in postembryonic mesoderm progenitors, probably through suppression of sem-2; Belongs to the formin homology family.
      
 0.759
tbx-37
Putative T-box protein 37.
   
 
 0.741
lim-6
LIM domain family.
   
 
 0.721
che-1
Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36.
      
 0.699
nsy-4
Neuronal SYmmetry.
      
 0.691
inx-19
Innexin-19; Structural component of the gap junctions that specifically coordinates left-right asymmetry in the developing nervous system. Acts by forming gap junction network linking embryonic neurons and providing electrical coupling between cells, leading to promote or inhibit AWC signaling. Required for the left and right AWC olfactory neurons to establish asymmetric patterns of gene expression during embryogenesis. Acts autonomously.
      
 0.663
lsy-13
PHD domain-containing protein.
    
 
 0.584
H10D18.5
Uncharacterized protein.
    
 
 0.553
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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