STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxa-136F-box A protein. (1881 aa)    
Predicted Functional Partners:
F14F9.4
Uncharacterized protein.
      
 0.850
clec-163
C-type LECtin.
      
 0.850
wht-3
ABC transporter ATP-binding protein/permease wht-3; Required for efficient RNA interference (RNAi) of pop-1 indicating a role in the germline development. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
      
 0.808
fbxa-116
F-box domain-containing protein.
      
 0.698
parg-2
Poly(ADP-ribose) glycohydrolase 2; Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells (By similarity).
      
 0.697
C15B12.8
DAO domain-containing protein.
      
 0.616
twk-35
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.536
twk-33
TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.536
elo-6
Elongation of very long chain fatty acids protein 6; Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) and monomethyl branched-chain fatty acids (mmBCFAs). Required for the formation of isoheptadecanoate (C17iso).
      
 0.513
kcnl-4
CaMBD domain-containing protein.
      
 0.461
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.