STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C23H3.5DUF4477 domain-containing protein. (403 aa)    
Predicted Functional Partners:
C08B6.8
Probable oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
   
    0.536
dars-2
AA_TRNA_LIGASE_II domain-containing protein.
   
    0.491
K04F10.3
Endoplasmic reticulum-like protein.
   
    0.437
gro-1
tRNA isopentenyl transferase; Belongs to the IPP transferase family.
   
    0.434
smg-7
TPR_REGION domain-containing protein.
   
    0.432
M04B2.2
THUMP domain-containing protein.
   
    0.426
Y39A1A.14
Ribosomal RNA small subunit methyltransferase nep-1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates a pseudouridine in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3- carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre- ribosomes; Belongs to the class IV-like SAM-binding methyltransferase superfami [...]
   
    0.420
ZK632.11
Uncharacterized protein ZK632.11.
   
    0.412
vars-1
Valyl Amino-acyl tRNA Synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
    0.400
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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