STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
che-6Cyclic nucleotide-binding domain-containing protein. (655 aa)    
Predicted Functional Partners:
tax-2
Cyclic nucleotide-binding domain-containing protein.
  
0.918
cng-3
Cyclic nucleotide-binding domain-containing protein.
  
 
0.682
kvs-4
Probable voltage-gated potassium channel subunit kvs-4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes.
   
  
 0.666
best-24
Bestrophin homolog 24; Forms chloride channels.
      
 0.663
tax-4
Cyclic nucleotide-gated cation channel; Required for normal thermosensation and chemosensation sensory behavior. Required, downstream of receptor- type guanylate cyclase gcy-9, for CO2-mediated responses in BAG neurons. Required, downstream of receptor-type guanylate cyclase gcy-14, for alkaline pH-mediated responses in ASE-left (ASEL) neurons. Involved in the development of ASJ sensory neuron axon during late larval stages and in the maintenance of normal axon morphology in the adult. Regulates dauer formation. Required for the calcium flux to the cytoplasm in the ASJ sensory neurons [...]
  
 
0.661
cng-1
Cyclic nucleotide-binding domain-containing protein.
  
  
0.638
cng-2
Cyclic nucleotide-binding domain-containing protein.
  
 
0.571
ncs-4
Neuronal Calcium Sensor family.
   
  
 0.520
cal-2
CALmodulin related genes.
     
 0.516
sec-8
Exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
     
 0.505
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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